Introduction: Side effect of Dupixent. Dupixent is a medication used to treat various inflammatory conditions, primarily atopic dermatitis (eczema) and asthma. While it can effectively manage these conditions, it can cause side effects.
Some side effects are common, while others are less frequent but more severe. It’s vital to note that not everyone will experience these side effects, and some individuals may have no side effects at all. Dupixent can cause specific side effects (also called adverse effects), some more common than others.
These side effects may be fleeting, lasting a few days or weeks. But if side effects last longer than this, bother you, or become severe, be sure to talk to your doctor or pharmacist.
This article provides a comprehensive understanding of the potential side effects associated with Dupixent.
Common side effects
Many individuals who use Dupixent may experience mild injection site reactions. These reactions can include pain, redness, swelling, or itching at the njectioarticle toms, which are usually not severe and tend to resolve independently within a few days.
Conjunctivitis (Pink Eye):
Conjunctivitis, or pink eye, is a more common side effect of Dupixent. It involves inflammation of the eye’s outer membrane. Symptoms of conjunctivitis may include redness, itching, and discharge from the looks. This side effect can be uncomfortable but is typically manageable.
Oral Herpes:
Some patients taking Dupixent may experience an increased frequency of cold sores caused by the herpes simplex virus. While this side effect can be bothersome, it is generally not severe.
The most common side effects include:
Eczema: injection site reactions, inflammation of the eye and eyelids, including redness, swelling, and itching, sometimes blistering, cold sores on your mouth or lips, and an increase in a specific white blood cell (eosinophilia).
Asthma: Injection site reactions, eosinophilia, oropharyngeal pain, and helminth infections.
Chronic rhinosinusitis with nasal polyposis: injection site reactions, inflammation of the eye and eyelids, including redness, swelling, and itching, sometimes blurred vision, high numbers of specific blood cells (eosinophilia), gastritis, joint pain (arthralgia), difficulty sleeping (insomnia), and toothache.
Eosinophilic Esophagitis: Injection site responses, upper respiratory tract infections, cold sores in your jaws or lips, and joint pain (arthralgia).
Prurigo nodularis: Inflammation of the eye and eyelids, including redness, swelling, itching, sometimes blurred vision, herpes virus infection, common cold symptoms (nasopharyngitis), dizziness, muscle pain, and diarrhea.
Tell your healthcare provider about any side effects that bother you or do not disappear. These are not all potential side effects of Dupixent. Call your physician for medical guidance about side effects. You are encouraged to report adverse side effects of prescribed medications to the FDA.
Upper Respiratory Tract Infections
Upper respiratory tract infections, such as the common cold, may occur more frequently in individuals using Dupixent. Symptoms include a runny or stuffy nose, sneezing, or a sore throat. These infections are generally mild and self-limiting.
Headache:
Headaches are another relatively common side effect of Dupixent. However, these headaches are generally mild and temporary. They often resolve without the need for additional treatment.
Injection Site Eczema:
Individuals may sometimes experience eczema-like skin reactions at the injection site. These skin symptoms are usually not severe and can be managed with appropriate skincare.
Eye and Vision Problems:
Dupixent may lead to mild eye and vision problems in some individuals. Symptoms can include blurry vision, eye pain, or other vision disturbances. These side effects are usually manageable and do not result in long-term issues.
Rare but severe side effects
Dupixent can cause serious side effects, including:
Allergic reactions. Dupixent can generate allergic reactions that can sometimes be severe. Stop using Dupixent and tell your healthcare provider or get emergency help right away if you notice any of the following signs or symptoms: difficulty breathing or wheezing, face, Swelling of the lips, mouth, tongue, or throat, fainting, dizziness, feeling light-headed, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or pain in your abdominal area.
Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurriness. Your healthcare provider may refer you to an ophthalmologist for an exam if needed.
Inflammation of your blood vessels. Infrequently, this can occur in people with asthma who acquire Dupixent. This may occur in people taking oral steroid medication that is being stopped or the dose reduced. It is not known if Dupixent causes this.
Tell your healthcare provider immediately if you have a rash, chest pain, trouble breathing, pins and needles sensation, numbness in your arms or legs, or persistent fever.
Joint aches and pains. Some people who use Dupixent have common symptoms that cause difficulty walking or walking; some cases require hospitalization. Notify your healthcare provider about any new or degenerating joint symptoms. Your healthcare provider may stop Dupixent if you develop common symptoms.
Although rare, severe allergic reactions can occur with Dupixent. Signs of a severe allergic reaction include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. Severe allergic reactions can be life-threatening and need immediate medical attention. It is essential to seek emergency medical care if these symptoms occur.
Long-term side effects
A clinical trial showed that the side effects of duplexing were similar whether the drug was used short-term or long-term. Most of the side effects that Dupixent causes are short-term.
But in rare cases, the drug can cause side effects that can be long-lasting. These contain eye-related side effects, such as transitions in vision and new or worsening eye conditions. Long-term side effects may also include eosinophilic diseases such as vasculitis (swelling and inflammation of blood vessels).
Dupixent may increase the risk of bacterial infections. Individuals taking Dupixent should be vigilant for signs of infection, such as fever, chills, or a persistent cough. These signs should be promptly reported to a healthcare provider.
Parasitic Infections:
A slightly increased risk of parasitic infections is associated with Dupixent, particularly in areas with more prevalent conditions. It’s essential to be aware of this hazard and take appropriate precautions.
Malignancies:
Ongoing research: Long-term safety data on Dupixent are still being studied, so there is some uncertainty regarding the risk of malignancies (cancers). Discussing this aspect with your healthcare provider and considering the potential benefits and risks of using Dupixent for your specific condition is essential.
Gastrointestinal Disorders
Some individuals may experience gastrointestinal issues while taking Dupixent. These can include diarrhea, nausea, or vomiting. While these symptoms can be uncomfortable, they are manageable and not severe.
It’s crucial to have an open and honest discussion with your healthcare provider before starting Dupixent to fully understand the potential side effects and weigh them against the benefits of the medication.
Additionally, if you experience severe or unusual side effects while using Dupixent, it is essential to contact your healthcare provider promptly for guidance and possible adjustments to your treatment plan.
Indications
Dupixent is a prescription medicine used to:
- To treat adults and children six months of age or older with moderate to severe eczema (atopic dermatitis or AD) that is not well controlled with prescription treatments used on the skin (Ticle). , or who cannot use topical therapies. Dupixent may be used with or without topical corticosteroids. It is unknown whether Dupixent is safe and effective in children younger than six months of age with atopic dermatitis.
- Treating moderate to severe eosinophilic or oral steroid-dependent asthma with other asthma medications in adults and children six years of age and older whose asthma is not controlled by their current asthma medications. Dupixent helps prevent severe asthma attacks (anxiety) and may improve your breathing.
- Dupixent can also help you reduce the oral corticosteroids you take while preventing severe asthma attacks and improving your breathing. Dupixent is not used to treat hurried breathing problems. Whether Dupixent is safe and effective in children under six with asthma is unknown.
- With other drugs for the maintenance treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is uncontrolled. Whether Dupixent is safe and effective in children younger than 18 with chronic rhinosinusitis with nasal polyposis is unknown.
- For treating adults and children 12 years of age and older, weighing at least 88 pounds (40 kg), with eosinophilic esophagitis (EoE). It is not known whether Dupixent is safe and effective in children with eosinophilic esophagitis who are younger than 12 years of age and who weigh at least 88 pounds (40 kg).
- Treating adults with prurigo nodularis (PN). It is not known whether Dupixent is safe and effective in children younger than 18 years with prurigo nodularis.
Conclusion: Side effect of Dupixent
Like most medicines, Dupexant can cause side effects. Most of the side effects caused by Dupixent are mild and usually go away independently. However, some rare but severe side effects have been reported by people using the drug in clinical trials. Talk to your doctor or pharmacist if you want to know about Dupixent.
They can help answer any questions you may have about the side effects of taking the medication. It is not known if Dupixent is safe to use during pregnancy. You may want to join a pregnancy registry if you and your doctor agree that using medicine while pregnant is the best option. The registry monitors the health of people who use duplexing during pregnancy.
Also read: Side Effects of Olumiant; Side effect of octreotide; Side Effects of EpiPens
This post is also available in:
English
